Search results for "intestinal microflora"
showing 8 items of 8 documents
Immunosenescence and anti-immunosenescence therapies: the case of probiotics.
2008
ABSTRACT Aging is a complex process that negatively impacts the development of the immune system and its ability to function. Progressive changes in the T and B cell systems over the life span have a major impact on the capacity to respond to immune challenge. These cumulative age-associated changes in immune competence are termed immunosenescence. This process is mostly characterized by: (1) shrinkage of the T cell repertoire and accumulation of oligoclonal expansions of memory/effector cells directed toward ubiquitary infectious agents; (2) involution of the thymus and the exhaustion of naive T cells; and (3) chronic inflammatory status. Here we discuss possible strategies to counteract t…
INTESTINAL BACTERIA AND BOWEL DISEASE: ROLE OF PROBIOTICS.
2010
The gut of a helathy adult harbours a myriad of different microbial species (aproximately 10.14 colony forming units). In healthy adults the main control of intestinal bacterial colonization occurs through the gastric acidity. Moreover, other factors can influence the intestinal micorenvironment, as pH, temperature, competition among different bacterial strains, peristalsis, drugs, radiotherapy, and much more. It was found that, when you have an impaired micorbial homeostasis, the intestinal microsystem becomes unstable, so that leads to an alteration of the permeability of tissues, togheter with the activation of the intestinal immune system (MALT). These microenvironmental changes thus pr…
Treatment of irritable bowel syndrome with probiotics. An etiopathogenic approach at last?
2009
Irritable bowel syndrome (IBS) is the most common functional digestive disorder, and may affect 11-20% of the adult population in industrialized countries. In accordance with Rome III criteria (2006) IBS involves abdominal pain and bowel habit disturbance, which are not explained by structural or biochemical abnormalities. Several hypotheses attempt to account for the pathophysiology of IBS, but the etiology still remains uncertain or obscure, perhaps multifactorial. Abnormalities in colonic microflora have recently been suggested in such patients, as has abnormal small-intestine bacterial overgrowth (SIBO), or in particular a significant reduction in the amount of intraluminal Bifidobacter…
Corrective factors of intestinal microflora disorders in the perinatal period
2019
Intestinal microflora is found at approximately 104 bacteria per ml of intestinal fluid. Although this ecosystem is very diverse with dynamic changes taking place within it, there is a certain stability in the type and number of species, referred to as the core microbiome, found in 95% of the human population. Genetic variation of microorganisms is relatively small, and their functions are strictly defined and highly conservative. The microbiome exists symbiotically with the host, protecting it against colonization by pathogenic microorganisms, providing essential metabolites, and stimulating the immune system. Colonization begins prenatally and its development is greatly influenced by the …
From gut microflora imbalance to mycobacteria infection: is there a relationship with chronic intestinal inflammatory diseases?
2011
The gut of a healthy adult harbours a myriad of different microbial species. It is estimated that approximately 10 14 are present in total bacterial colony forming units (CFU). Each colony colonizes a specific intestinal tract. In healthy adult, the main control of intestinal bacterial colonization occurs through gastric acidity but also other factors can influence the intestinal microenvironment such as pH, temperature, competition among different bacterial strains, peristalsis, drugs, radiotherapy and much more. Impaired microbial homeostasis leads to an alteration of the permeability of tissue, together with the activation of the intestinal immune system MALT (mucosal associated lymphoid…
Probiotiku izvēle atopiskā dermatīta gadījumos
2018
Alerģijas epidēmijas veicināšanā lielu lomu spēlē mūsdienu attīstītās sabiedrības dzīvesveids, kuru raksturo mikrobiālas floras nomākšana, tā izmainot cilvēka mikrobiotu un negatīvi ietekmējot imūno regulāciju (Fiocchi et al 2015). Maģistra darba mērķis bija noskaidrot dermatologu viedokli par atopisko dermatītu, ņemot vērā ārstēšanas vadlīnijas, un, izanalizējot zinātniskās publikācijas, izpētīt atopiskā dermatīta ārstēšanas tendences Latvijā, un izpētīt probiotiķu lomu atopiskā dermatīta profilaksē. Anketas aizpildīja ārsti – dermatologi (praktizējošie ārsti). Datu analīzei tika izmantotas 70 aptaujas. Secinājumi: Atopiskā dermatīta ārstēšanā visbiežāk izvēlas topiski lietojamos glokokort…
The intestinal ecosystem and probiotics
2016
The term "probiotic" comes from the greek "pro bios" and means "pro life": Nowadays, an increasing number of pharmaceutical preparations and functional foods are enriched with probiotics and for the patients it is increasingly important to receive information needed to know how to orient in the choice. The benefits from probiotics are many and include the modulation of the intestinal microflora (stimulation of beneficial bacteria and inhibition of pathogens), the support of bowel function and the stimulation of the immune system. This broad spectrum of beneficial effects to maintain efficient the intestinal ecosystem. Therefore, probiotics are an useful tool to prevent the formation of diso…
Impact of Oat-Based Products on Human Gastrointestinal Tract
2015
Abstract Oat is rich in valuable nutrients. In comparison to other cereals, oat contains more total proteins, carbohydrate, fat, non-starch fibre, as well as unique antioxidants (one of them - avenanthramides), vitamins, and minerals. One of the most often studied components of oats is β-glucan - a type of soluble dietary fibre located throughout the starch endosperm, but with highest concentration in the bran. Many studies have shown the beneficial health effects of oat β-glucan as a soluble dietary fibre. Until now, most of the studies on this nutrient have been conducted in the cardiovascular and diabetology field. This article aimed to review the literature on studies that investigated …